The main research work of the Centre can be summarised under the following headings:
Current and recent research
- Prenatal identification of trisomy 18 (Edwards syndrome), a thesis by Glenn Palomaki
- Preliminary results of selected work in progress on Antenatal Screening
- Folic acid supplementation, from neural tube defects to heart disease
- Antenatal screening for Down's syndrome and neural tube defects
- Antenatal couple screening for cystic fibrosis
- Stomach cancer: a randomised trial of screening for Helicobacter pylori infection
- Hip fracture: can it be prevented?
- Prevention of cardiovascular disease
- Aortic aneurysm screening
- Use of the Down's Syndrome Register as a public health and research facility
- Pathogenesis of disease: causes, risk factors and thresholds
- Screening methodology:
- antenatal screening - the estimation of screening performance
- combining many tests into one
- Homocysteine and cardiovascular disease
- Aspirin and colon cancer
- Growth factors and cancer
- Blood pressure: a policy for the drug treatment of high blood pressure - reduce BP, rather than measure it
- Very premature babies: investigation of the outcomes and their antecedents from a national cohort (EPIcure).
- Is screening adults for hypothyroidism worthwhile? - A randomised crossover trial
Past research
- Breast cancer
- Prostate cancer screening: is it better to measure bound and free PSA?
- Chlamydia infection and heart disease: epidemiological evidence against an interesting hypothesis