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TADAH

Centre for Cancer Prevention

Project Investigator:  Dr Karly Louie

Overview

The TADAH Study aims to evaluate the feasibility of of detecting Human papillomavirus (HPV) antibodies in dried blood spot (DBS) and oral mucosal transudate (OMT) vs. venous blood sera to confirm HPV vaccination status.

In the UK, there is a routine national HPV immunisation programme to vaccinate girls aged 12-13 years old. HPV vaccination aims to prevent women from developing cervical cancer. However, because of the long period of time required for an HPV infection to develop into cervical cancer, it will be several decades before we can fully assess the vaccine’s impact on health. Data suggest that about 10% of women are unsure about their HPV vaccination status and vaccination history are poorly recorded in a woman’s GP record. Therefore, a test to confirm a woman’s vaccination status is needed to rationalise changes in the cervical cancer prevention strategies in the future (e.g. different intervals of screening for fully vaccinated vs. unvaccinated).

Results from TADAH will identify the best and most acceptable acceptable to test to confirm a woman's HPV vaccination status.

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