Wolfson Institute of Preventive Medicine

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Statistical research for clinical trials

Centre of Cancer Prevention

Project Investigator: Peter Sasieni


The following problems are being actively studied:

  • Design and analysis of multi-arm clinical trials. There is particular interest in adaptive designs in which arms are dropped.
  • Design and analysis of clinical trials with factorial designs to study multiple interventions in a single trial.
  • Analysis of clinical trials subject to non-compliance and unplanned cross-over.
  • Design of predictive biomarker trials to detect a qualitative interaction.

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