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Ramdomised trial of nicotine patch preloading for smoking cessation

Centre of Environmental and Preventive Medicine

Funding Body: National Institute for Health Research
Project Investigator: Peter Hajek


An open label pragmatic randomised controlled trial of nicotine preloading for smoking cessation

This study aims to examine the relative efficacy, safety and cost effectiveness of standard NHS stop-smoking treatment versus standard treatment plus nicotine patch worn for 4 weeks prior to quitting. The primary outcome measure is 6 month prolonged abstinence.

The study is a collaboration between QMUL, University of Oxford, University of Birmingham, University of Bristol and University of Nottingham.

Using nicotine patches prior to stopping smoking may make cigarettes less rewarding and facilitate quitting. The trial is evaluating this notion.

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