Wolfson Institute of Preventive Medicine

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Overview of SERM breast cancer prevention trials

Centre for Cancer Prevention

Project Investigator:  Professor Jack Cuzick


Overviews of all the SERM breast cancer prevention trial using tamoxifen, raloxifene, lasofoxifene, or arzoxifene. Recent overview provides clear evidence for extended benefits and minimal side effects in the five years following active treatment with these agents.  

Recent work also involves review of the use of aromatase inhibitors for adjuvant treatment with plans to also look at them in prevention.



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