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Evaluation of HPV Primary Screening Pilot

Centre for Cancer Prevention

Funding Body: NHS Cancer Screening Programme
Project Investigator:  Professor Sue Moss


Human papilloma virus (HPV) testing as a primary screening method is expected to be more sensitive than cytology, and by virtue of extending screening intervals and use of less manpower, may be more cost effective.

A pilot of HPV testing as primary screening is now to be implemented in six sites in England. These sites previously acted as sentinel sites for HPV triage of women with borderline/mild cytology, which is currently being rolled out throughout the NHS Cervical Screening Programme (NHSCSP).

The sites will follow the protocol agreed by the NHSCSP HPV Primary Screening Pilot Group.

The aims of the evaluation of the pilot are to study the effect of the introduction of HPV primary screening on key outcome measures including uptake/coverage of cervical screening, rates of referral to colposcopy, rates of compliance with recall and detection rates of disease.

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