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TransATAC

Centre for Cancer Prevention

Project Investigator:  Professor Jack Cuzick

Overview

Biomarker study of most UK patients in the ATAC trial.

A range of IHC, FISH and expression profile marker panels have been studied. Combination of IHC for ER, PgR, ki67 and FISH for Her2 used to create IHC4 panel. Several expression profile panels evaluated including Oncotype, Pam50 (Prosigna) and, BCI.

Our current focus is on markers for late recurrence. Original blocks being recollected for further studies.

 

 

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